Tentative Term Presentation Topics: 1) Comparative genomics and applications David Gonzalez and Yuwei Zhang, 5/21, talk 3 2) Metagenomics and comparative metagenomics 3) Gene regulatory networks and modules Deepak Reddy and Rahul Yenduri, 6/4, talk 3 4) Computational approaches for functional genomics Pedram Zaree and Chao Wu, 6/6, talk 1 5) RNA secondary structure prediction  Varun Narayanan and Nithya Thushara Krishna Pothula, 5/23, talk 3 6) Small RNAs, microRNAs and other noncoding RNAs 7) Protein secondary structure determination Sreekar Praneeth Marri and Venkata Ranga Sai Vishal Matcha, 5/23, talk 1 8) Protein tertiary structure determination (or protein folding), especially recent breakthroughs including AlphaFold/RoseTTAFold Chaitanya Ananda and Erfan Shayegani, 6/4, talk 1 9) Protein-protein (or protein-drug) interactions Ajay Virupaksha, 6/10, talk 5 10) Peptide sequencing/identification by mass spec Xinyu Zhang and Xingyan Zhou, 6/4, talk 2 11) Molecular dyanmics modeling and simulation 12) SNPs and haplotype inference 13) Genome-wide association studies (GWAS) 14) Disease gene prioritization based on networks of genes and diseases Ravi Theja Tangirala and Bhargavi Rengarajan, 5/23, talk 2 15) Genetic drug discovery and combinatorial chemistry 16) Drug repositioning and repurposing with applications in COVID-19 Neeha Gajula and Nikhil Mahendrakar, 5/28, talk 1 17) Representation, simulation, and inference of gene networks and pathways 18) Next generation resequencing (NGS) technologies (DNA-Seq, RNA-Seq, ChIP-Seq, DNase-Seq, ATAC-Seq, SHAPE-Seq, CLIP-Seq, etc) on Illumina/Solexa, 454, SOLiD, SMRT, Nanopore, etc. platforms and their data analysis; multiple non-overlapping talks are possible Joseph Rodriguez and David Stratham, 6/10, talk 1 19) Genome assembly from NGS short reads, de Bruijn graphs Edgar Melendrez and Tyler Pastor, 5/30, talk 1 20) Transcriptome assembly and abundance quantification Huy Tran and Weihang Kuang, 5/28, talk 3 21) Computational challenges in epigenomics Jordan Peck and Bowen Qi, 6/6, talk 3 22) Computational prediction of chromosomal structures using Hi-C, ChIA-PET, etc 23) Single cell technologies (sequencing, gene expression, etc) and data analysis Rohith Reddy K and Ravi Teja N, 6/6, talk 2 24) Spatial (or 4D) genomics Bo Huang and Jordan Chan, 5/30, talk 3 25) Integration of multi-omics data Fengchun Fan and Yusen Zhang, 5/21, talk 2 26) The ENCODE project and its key findings/data Sun Hye Baek and Viha B Raju, 6/10, talk 3 27) Analysis of medical (such as CT, MRI, X-ray, etc.) images Vasanthakumar Shanmugavadivel and Sruthi Suresh, 5/28, talk 2 28) Genomics and human health, immunotherapy, etc. Vishal Rohith Chinnam and Aswini Shilpha S S, 5/30, talk 2 29) Evolution of viruses (e.g., SARS-CoV-2) Akhila Gudumani and Yuktha Polepalli, 6/10, talk 2 30) A deeper treatment of some topic covered in class such as the complexity of PDP, gene/exon prediction, sequence assembly, phylogenies, etc. 31) An interesting extension/observation/revision on some technical result discussed in class or the textbooks 32) A comparison between combinatorial and statistical approaches for solving the same problem Aaryan Bhagat and Sakthi Kumar Sampath Kumar, 6/10, talk 4 33) Other interesting topics that I have missed in the above, e.g. suffix arrays, BW/FM transformations, etc. Each topic will be presented by a team of two students. Ideally, a presentation should begin with (1) the biological background, (2) an overview of computational problems, (3) a survey of algorithmic approaches for solving the problems, and then (4) some discussion of one or two of the approaches in more depth. Every team should prepare to read 3 to 5 papers, speak for about 20 minutes and answer questions for about 4 minutes at the end of the presentation. The presentations will begin on Tuesday May 21 and end on Monday June 10. We can accommodate three teams in a regular lecture and up to 7 teams in the final exam slot. Please let me know your team members, selection of the topic and the date you'd prefer to present ASAP. Remember that the earlier you choose, the more choices you will have :-) Note that you are supposed to create your own slides for the presentation, but if you have to borrow some material from somewhere (e.g., figures, tables, or sometimes entire slides), you must cite the sources explicitly.